Liposomal Magnesium Glycinate
Appearance: White to off-white, free-flowing fine powder with low hygroscopicity.
Solubility/Dispersibility: Instantly disperses in cold water to form a homogeneous, sediment-free suspension with a clean mouthfeel.
Particle Size (DLS): Uniform sub-micron distribution, engineered for cellular uptake and stable suspension.
Encapsulation Efficiency: 80%–95% of the chelated magnesium retained inside the phospholipid bilayer.
Stability: Protects the chelate from dissociation in the gastric environment and from moisture uptake during storage; 24-month shelf life.
Minerals | Chelated Magnesium | Sleep & Stress Support | OEM Available
Description
Liposomal Magnesium Glycinate Powder: Bulk Supply for Sleep, Stress and Recovery Formulas
Magnesium is the fourth most abundant mineral in the body and the cofactor for more than 300 enzymatic reactions, yet a large share of adults in Western markets fail to meet the recommended intake. The commercial problem has never been convincing consumers that they need magnesium—it is delivering a dose high enough to matter without the digestive consequences that make people stop taking it.
Liposomal Magnesium Glycinate from EmerWell Bio combines two complementary strategies. Magnesium bisglycinate is a fully chelated mineral with 14.1% elemental magnesium by mass in its anhydrous form, inherently gentler on the gut than oxide or citrate salts. Encapsulating that chelate in a phospholipid vesicle on the EncapsWell™ platform adds gastric protection, sustained release and clean water dispersibility—so a 400 mg elemental magnesium serving fits in two capsules or a single stick pack.
Produced in cGMP-certified facilities under ISO 22000 and FSSC 22000, with full traceability from chelate to finished powder.
- Sleep Quality & Relaxation
- Stress Response & Nervous System
- Muscle Function & Recovery
- Bone & Cardiovascular Support
Why Liposomal Delivery Matters for a Chelated Mineral
Magnesium glycinate is already the premium form in this category—so it is fair to ask what encapsulation adds. Three things, all of which show up in the finished product:
First, tolerance at high dose. Unabsorbed magnesium draws water into the intestinal lumen. That is the mechanism behind the laxative reputation of magnesium oxide and, at higher servings, of citrate. Because the chelate is stabilized inside a lipid vesicle and released gradually rather than dumped into the small intestine at once, the osmotic load per unit time is lower. Formulas built on our powder can therefore carry 300–400 mg of elemental magnesium per serving without the "start low" instruction that consumers ignore.
Second, fewer mineral interactions. Free magnesium ions compete with calcium and iron for shared transport pathways. Encapsulated magnesium travels as a vesicle rather than as a dissolved ion, which reduces that competition in multi-mineral formulas—an important detail for bone-health and prenatal products where all three minerals appear on the same label.
Third, the glycine itself. Glycine is an inhibitory neurotransmitter and the second component of the chelate. Formulators increasingly position magnesium glycinate in the sleep and stress category rather than the general-mineral category, and the liposomal matrix supports that positioning by extending release across the evening rather than peaking and clearing within two hours.
Technical Specifications of Liposomal Magnesium Glycinate
| Parameter | Specification |
|---|---|
| Appearance | White to off-white, free-flowing fine powder |
| Elemental Magnesium | 10%–14% (customizable); theoretical maximum for anhydrous bisglycinate is 14.1% |
| Magnesium Source | Magnesium bisglycinate (fully chelated); buffered grades available on request |
| Chelation Rate | ≥ 95% (by titration) |
| Particle Size (DLS) | Sub-micron, uniform distribution; D50 customizable |
| Encapsulation Efficiency | 80%–95% |
| Moisture | ≤ 5.0% |
| Bulk Density | 0.35–0.55 g/mL (tapped), grade dependent |
| Heavy Metals | Pb < 0.5 ppm; As < 0.5 ppm; Cd < 0.3 ppm; Hg < 0.1 ppm |
| Microbiology | TPC < 1000 cfu/g; yeast & mold < 100 cfu/g; E. coli and Salmonella negative |
| Certifications | cGMP, ISO 9001, ISO 22000, FSSC 22000, HACCP, Kosher, Halal, Non-GMO, Vegan |
| Packaging | Nitrogen-flushed multi-layer foil bags: 1 kg sample / 25 kg standard |
Values above are standard manufacturing targets. The binding specification for each lot is stated on its Certificate of Analysis.
Health Benefits & Applications
Sleep Quality and Relaxation
Magnesium supports GABAergic signaling and helps regulate the hypothalamic-pituitary-adrenal axis; glycine has separately been studied for sleep-onset latency. A chelate that supplies both, released across the evening, is the most defensible label story in the sleep category—and one that does not depend on a melatonin claim.
Stress Response and Nervous System
Under chronic stress, urinary magnesium excretion rises, which is one reason low status and high stress tend to co-occur. Positioned with L-theanine or ashwagandha, liposomal magnesium glycinate anchors the "calm focus" segment without sedative framing.
Muscle Function and Recovery
Magnesium is required for ATP hydrolysis in the muscle fiber and for calcium reuptake during relaxation. Endurance athletes lose magnesium through sweat, and cramping is the consumer-facing signal most likely to drive repeat purchase.
Bone and Cardiovascular Support
Roughly 60% of body magnesium resides in bone. Combined with vitamin D3 and K2—both of which we supply in liposomal form—magnesium glycinate completes a bone-health triad that formulators can build as a single SKU.
Commercial Applications for Wholesale Liposomal Magnesium Glycinate
Capsules and Tablets
High elemental load per gram means a 200 mg serving fits in a single size-0 capsule, and a 400 mg serving in two—without the eight-capsule regimens that oxide-based products require.
Powders and Stick Packs
Clean dispersion with minimal sediment and a mild, low-salinity taste profile. Suitable for evening drink mixes, magnesium-glycine blends and electrolyte formulas.
Gummies and Chewables
Encapsulation masks the chalky, slightly metallic note of dissolved magnesium salts, which is the usual reason gummy formulas fail sensory panels.
Multi-Mineral and Prenatal Formulas
Reduced competition with calcium and iron makes this grade practical in combination products where mineral loading is otherwise a formulation headache.
Why EmerWell's Liposomal Magnesium Glycinate Stands Apart
A Defined Chelate, Not a Blend
Many "magnesium glycinate" powders on the market are buffered with magnesium oxide to reach a target elemental percentage. We declare the chelation rate and the source on the specification sheet, so the number on your label matches the chemistry in the drum.
Particle Engineering for Suspension Stability
Uniform sub-micron vesicles resist sedimentation, which is what allows a liquid or stick-pack format to hold its dose to the end of shelf life rather than settling into a layer at the bottom.
cGMP Manufacturing with Dual Testing
Every batch is assayed in-house and verified by an independent laboratory. Elemental magnesium is confirmed by complexometric titration, not calculated from raw material inputs.
Applications Support in San Diego
Our PhD team will run dispersion, taste and stability trials against your base before you commit to a production quantity.
Quality Assurance You Can Verify
- Independent Certificate of Analysis for every lot
- MSDS, technical data sheet and chelation rate statement
- Particle size distribution (DLS) report
- 24-month stability data
- Heavy metal and microbiological testing by a third-party laboratory
- Allergen, Non-GMO and vegan statements
Seamless Integration Into Your Product Line
- Free samples: 1 kg pilot packs for sensory and dispersion trials.
- Customization: elemental magnesium 10%–14%, particle size, carrier system and taste profile.
- Documentation: regulatory packages for US, EU and APAC markets.
- Response time: 24-hour technical response from our US-based team.
Frequently Asked Questions
Q: How much elemental magnesium does your powder contain?
A: Standard grades carry 10%–14% elemental magnesium. Fully chelated anhydrous magnesium bisglycinate has a theoretical maximum of 14.1%; buffered commercial grades typically sit near 10%. We declare the exact figure on the COA rather than quoting a range on the label.
Q: How is this different from your standard Liposomal Magnesium Powder?
A: The standard grade is a multi-salt platform (bisglycinate, citrate or oxide) covering 5%–25% elemental magnesium. This page is the dedicated bisglycinate grade: fully chelated, higher elemental load, and positioned for sleep, stress and multi-mineral formulas where tolerance and mineral competition matter.
Q: Will liposomal encapsulation really reduce the laxative effect?
A: The glycinate chelate is already the gentlest common form. Encapsulation adds gradual release, which lowers the osmotic load in the intestinal lumen at any one time. In practice this means higher single-serving doses are better tolerated, though individual response still varies.
Q: Can it be used in a clear beverage?
A: Yes. The powder disperses to a translucent-to-opaque colloidal suspension depending on concentration. If you need a fully transparent drink, ask us about our low-opacity grade before finalizing the formulation.
Q: Is the magnesium sourced from a non-animal origin?
A: Yes. The chelate is synthetic and the phospholipid carrier is vegetable-derived. The product is vegan and Non-GMO.
Q: What is the minimum order quantity?
A: 1 kg for samples and pilot trials; 25 kg for standard commercial packaging.
Q: Do you supply combination premixes?
A: Yes. We produce liposomal vitamin D3 + K2 and can build magnesium glycinate into a custom bone-health or sleep premix at your specified ratios.
Contact Us
Request a sample, specification sheet or dispersion trial for Liposomal Magnesium Glycinate at info@emerwell-bio.com. Our team responds within one business day.
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